|Security Name||Ticker||% of Net Assets|
|GILEAD SCIENCES INC||GILD||5.14%|
|VERTEX PHARMACEUTICALS INC||VRTX||3.42%|
|ALEXION PHARMACEUTICALS INC||ALXN||2.61%|
|SEATTLE GENETICS INC||SGEN||1.50%|
|BLUEBIRD BIO INC||BLUE||1.43%|
|SAGE THERAPEUTICS INC||SAGE||1.41%|
|NEUROCRINE BIOSCIENCES IN||NBIX||1.39%|
|IONIS PHARMACEUTICALS, IN||IONS||1.33%|
|JAZZ PHARMACEUTICALS PLC||JAZZ||1.30%|
|EXACT SCIENCES CORP||EXAS||1.25%|
|PRA HEALTH SCIEN||PRAH||1.24%|
|CHARLES RIVER LABORATORIES||CRL||1.18%|
|PROTHENA CORP PL||PRTA||1.18%|
|UNITED THERAPEUTICS CORP||UTHR||1.11%|
|LOXO ONCOLOGY IN||LOXO||1.00%|
|SYNEOS HEALTH INC||SYNH||1.00%|
|ARRAY BIOPHARMA INC||ARRY||0.95%|
|HALOZYME THERAPEUTICS INC||HALO||0.92%|
|ACADIA PHARMACEUTICALS IN||ACAD||0.91%|
|AMICUS THERAPEUTICS INC||FOLD||0.88%|
|GLOBAL BLOOD THE||GBT||0.79%|
|HORIZON PHARMA PLC||HZNP||0.79%|
|MYRIAD GENETICS INC||MYGN||0.75%|
|SPECTRUM PHARMACEUTICALS INC||SPPI||0.72%|
|SANGAMO THERAPEUTICS INC||SGMO||0.71%|
|RADIUS HEALTH IN||RDUS||0.67%|
|ACORDA THERAPEUTICS INC||ACOR||0.55%|
|FLEXION THERAPEUTICS INC||FLXN||0.48%|
|EAGLE PHARMACEUTICALS INC||EGRX||0.46%|
|AMAG PHARMACEUTICALS INC||AMAG||0.42%|
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) click here or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the investment management business of Guggenheim Partners, LLC ("Guggenheim"), which includes Security Investors, LLC ("SI"), Guggenheim Funds Investments Advisors, LLC ("GFIA") and Guggenheim Partners Investment Management ("GPIM") the investment advisors to the referenced funds.
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