Security Name | Ticker | % of Net Assets |
---|---|---|
ABBVIE INC | ABBV | 9.47% |
AMGEN INC. | AMGN | 6.16% |
GILEAD SCIENCES, INC. | GILD | 5.83% |
VERTEX PHARMACEUTICALS | VRTX | 4.45% |
REGENERON PHARMACEUTICALS | REGN | 3.65% |
CORTEVA INC | CTVA | 2.78% |
ASTRAZENECA PLC ADR | AZN | 2.56% |
ALNYLAM PHARMACEUTICALS | ALNY | 2.42% |
ROYALTY PHARMA PLC- CL A | RPRX | 2.06% |
INTRA-CELLULAR T | ITCI | 2.02% |
BIOGEN IDEC, INC. | BIIB | 1.91% |
NATERA INC | NTRA | 1.73% |
BIOMARIN PHARMACEUTICAL | BMRN | 1.67% |
INSMED INC | INSM | 1.64% |
EXELIXIS, INC. | EXEL | 1.44% |
INCYTE CORP | INCY | 1.42% |
HALOZYME THERAPEUTICS INC | HALO | 1.38% |
MODERNA INC | MRNA | 1.36% |
UNITED THERAPEUTICS CORP | UTHR | 1.36% |
NEUROCRINE BIOSCIENCES IN | NBIX | 1.36% |
JAZZ PHARMACEUTICALS PLC | JAZZ | 1.31% |
ALKERMES PLC | ALKS | 1.25% |
ILLUMINA INC | ILMN | 1.23% |
LEGEND BIOTECH CORP-ADR | LEGN | 1.21% |
VAXCYTE INC | PCVX | 1.19% |
VIATRIS INC | VTRS | 1.19% |
SAREPTA THERAPEU | SRPT | 1.19% |
ARGENX SE - ADR | ARGX | 1.17% |
TG THERAPEUTICS | TGTX | 1.11% |
BEIGENE LTD ADR | BGNE | 1.10% |
BRIDGEBIO PHARMA INC | BBIO | 1.07% |
REVOLUTION MEDICINES INC | RVMD | 1.06% |
AXSOME THERAPEUT | AXSM | 1.05% |
GUARDANT HEALTH INC | GH | 1.03% |
EXACT SCIENCES | EXAS | 1.01% |
MEDPACE HOLDINGS | MEDP | 0.99% |
BLUEPRINT MEDICI | BPMC | 0.96% |
CYTOKINETICS INC | CYTK | 0.96% |
CRISPR THERAPEUTICS AG | CRSP | 0.96% |
PTC THERAPEUTICS | PTCT | 0.95% |
IONIS PHARMACEUTICALS, IN | IONS | 0.94% |
SPRINGWORKS THERAPEUTICS | SWTX | 0.92% |
ROIVANT SCIENCES LTD | ROIV | 0.90% |
ADMA BIOLOGICS INC | ADMA | 0.88% |
BIONTECH SE-ADR | BNTX | 0.86% |
AVIDITY BIOSCIENCES INC | RNA | 0.83% |
ULTRAGENYX PHARM | RARE | 0.76% |
PROTAGONIST THER | PTGX | 0.75% |
AMICUS THERAPEUTICS INC | FOLD | 0.67% |
SUMMIT THERAPEUTICS INC | SMMT | 0.67% |
MADRIGAL PHARMAC | MDGL | 0.64% |
ACADIA PHARMACEUTICALS IN | ACAD | 0.63% |
APELLIS PHARMACE | APLS | 0.63% |
VIKING THERAPEUTICS INC | VKTX | 0.62% |
CRINETICS PHARMACEUTICALS | CRNX | 0.61% |
ASCENDIS PHA-ADR | ASND | 0.61% |
TWIST BIOSCIENCE CORP | TWST | 0.60% |
DYNAVAX TECHNOLOGY | DVAX | 0.60% |
RECURSION PHARMACEUTICALS | RXRX | 0.60% |
NUVALENT INC-A | NUVL | 0.60% |
KRYSTAL BIOTECH INC | KRYS | 0.56% |
VERACYTE INC | VCYT | 0.56% |
ARCELLX INC | ACLX | 0.54% |
BEAM THERAPEUTICS INC | BEAM | 0.54% |
ARROWHEAD PHARMACEUTICALS | ARWR | 0.50% |
IDEAYA BIOSCIENCES INC | IDYA | 0.48% |
DENALI THERAPEUT | DNLI | 0.46% |
NOVAVAX INC | NVAX | 0.46% |
CELLDEX THERAPEUTICS INC | CLDX | 0.45% |
IMMUNOVANT INC | IMVT | 0.40% |
AGIOS PHARMACEUT | AGIO | 0.39% |
INTELLIA THERAPE | NTLA | 0.35% |
IOVANCE BIOTHERAPEUTICS | IOVA | 0.29% |
GERON CORP | GERN | 0.29% |
DYNE THERAPEUTICS INC | DYN | 0.25% |
Other (Cash, derivatives and other liabilities) | 0.50% | |
Total: |
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Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, GS GAMMA Advisors, LLC, and Guggenheim Private Investments, LLC.
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