Security Name | Ticker | % of Net Assets |
---|---|---|
ABBVIE INC | ABBV | 7.00% |
GILEAD SCIENCES, INC. | GILD | 4.74% |
AMGEN INC. | AMGN | 4.65% |
VERTEX PHARMACEUTICALS | VRTX | 4.11% |
REGENERON PHARMACEUTICALS | REGN | 3.74% |
CORTEVA INC | CTVA | 3.61% |
ALNYLAM PHARMACEUTICALS | ALNY | 3.19% |
NATERA INC | NTRA | 2.28% |
BEIGENE LTD ADR | BGNE | 2.18% |
ASTRAZENECA PLC ADR | AZN | 2.17% |
BIOGEN IDEC, INC. | BIIB | 2.04% |
ROYALTY PHARMA PLC- CL A | RPRX | 1.97% |
EXACT SCIENCES | EXAS | 1.89% |
UNITED THERAPEUTICS CORP | UTHR | 1.83% |
EXELIXIS, INC. | EXEL | 1.81% |
NEUROCRINE BIOSCIENCES IN | NBIX | 1.78% |
ILLUMINA INC | ILMN | 1.76% |
INSMED INC | INSM | 1.62% |
VIATRIS INC | VTRS | 1.55% |
INCYTE CORP | INCY | 1.51% |
BIOMARIN PHARMACEUTICAL | BMRN | 1.48% |
ARGENX SE - ADR | ARGX | 1.35% |
MODERNA INC | MRNA | 1.33% |
BLUEPRINT MEDICI | BPMC | 1.33% |
REVOLUTION MEDICINES INC | RVMD | 1.30% |
BIONTECH SE-ADR | BNTX | 1.26% |
ALKERMES PLC | ALKS | 1.19% |
BRIDGEBIO PHARMA INC | BBIO | 1.15% |
HALOZYME THERAPEUTICS INC | HALO | 1.15% |
IONIS PHARMACEUTICALS, IN | IONS | 1.13% |
JAZZ PHARMACEUTICALS PLC | JAZZ | 1.10% |
GUARDANT HEALTH INC | GH | 1.08% |
ROIVANT SCIENCES LTD | ROIV | 1.08% |
ADMA BIOLOGICS INC | ADMA | 1.07% |
CRISPR THERAPEUTICS AG | CRSP | 1.07% |
MEDPACE HOLDINGS | MEDP | 1.04% |
TG THERAPEUTICS | TGTX | 1.03% |
LEGEND BIOTECH CORP-ADR | LEGN | 1.01% |
ACADIA PHARMACEUTICALS IN | ACAD | 0.90% |
AXSOME THERAPEUT | AXSM | 0.90% |
SUMMIT THERAPEUTICS INC | SMMT | 0.88% |
AVIDITY BIOSCIENCES INC | RNA | 0.87% |
SPRINGWORKS THERAPEUTICS | SWTX | 0.85% |
ULTRAGENYX PHARM | RARE | 0.85% |
VIKING THERAPEUTICS INC | VKTX | 0.83% |
CYTOKINETICS INC | CYTK | 0.82% |
PTC THERAPEUTICS | PTCT | 0.78% |
CRINETICS PHARMACEUTICALS | CRNX | 0.76% |
PROTAGONIST THER | PTGX | 0.73% |
VAXCYTE INC | PCVX | 0.73% |
ARROWHEAD PHARMACEUTICALS | ARWR | 0.72% |
VERACYTE INC | VCYT | 0.70% |
ASCENDIS PHA-ADR | ASND | 0.68% |
ARCELLX INC | ACLX | 0.66% |
NUVALENT INC-A | NUVL | 0.64% |
IDEAYA BIOSCIENCES INC | IDYA | 0.63% |
DENALI THERAPEUT | DNLI | 0.63% |
AGIOS PHARMACEUT | AGIO | 0.59% |
SAREPTA THERAPEU | SRPT | 0.59% |
APELLIS PHARMACE | APLS | 0.59% |
AMICUS THERAPEUTICS INC | FOLD | 0.59% |
RECURSION PHARMACEUTICALS | RXRX | 0.56% |
BEAM THERAPEUTICS INC | BEAM | 0.54% |
TWIST BIOSCIENCE CORP | TWST | 0.54% |
CELLDEX THERAPEUTICS INC | CLDX | 0.54% |
DYNE THERAPEUTICS INC | DYN | 0.53% |
MADRIGAL PHARMAC | MDGL | 0.52% |
NOVAVAX INC | NVAX | 0.51% |
INTELLIA THERAPE | NTLA | 0.48% |
DYNAVAX TECHNOLOGY | DVAX | 0.48% |
IMMUNOVANT INC | IMVT | 0.44% |
KRYSTAL BIOTECH INC | KRYS | 0.40% |
IOVANCE BIOTHERAPEUTICS | IOVA | 0.27% |
GERON CORP | GERN | 0.27% |
Other (Cash, derivatives and other liabilities) | 0.42% | |
Total: |
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Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, GS GAMMA Advisors, LLC, and Guggenheim Private Investments, LLC.
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