| Symbol | Company | Weighting |
|---|---|---|
| KRRO | KORRO BIO | 3.68% |
| RVMD | REVOLUTION MEDICINES INC | 3.65% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 2.81% |
| EWTX | EDGEWISE THERAPEUTICS | 2.42% |
| SNDX | SYNDAX PHARMACEUTICALS, INC. | 2.39% |
| TSHA | TAYSHA GENE THERAPIES I | 2.37% |
| XENE | XENON PHARMACEUTICALS | 2.36% |
| OCS | OCULIS HOLDING AG | 2.29% |
| AXSM | AXSOME THERAPEUTICS INC. | 2.15% |
| MRK | MERCK & CO. NEW | 2.07% |
| EYPT | EYEPOINT INC | 2.06% |
| DNLI | DENALI THERAPEUTICS INC. | 2.03% |
| PCVX | VAXCYTE INC | 2.01% |
| BMY | BRISTOL MYERS SQUIBB CO | 2.01% |
| TVTX | TRAVERE THERAPEUTICS INC | 1.94% |
| ALKS | ALKERMES INC | 1.87% |
| TNDM | TANDEM DIABETES CARE INC | 1.81% |
| AZN | ASTRAZENECA PLC | 1.81% |
| IONS | IONIS PHARMACEUTICALS INC | 1.76% |
| DYN | DYNE THERAPEUTICS, INC. | 1.73% |
| SLNO | SOLENO THERAPEUTICS INC | 1.72% |
| ALC | ALCON INC | 1.69% |
| MCK | MCKESSON CORP | 1.65% |
| GEHC | GE HEALTHCARE TECHNOLOGIES INC | 1.65% |
| ZTS | ZOETIS INC | 1.65% |
| IDYA | IDEAYA BIOSCIENCES, INC | 1.64% |
| HCA | HCA HOLDINGS INC | 1.63% |
| RVTY | REVVITY INC | 1.63% |
| ARQT | ARCUTIS BIOTHERAPEUTICS | 1.60% |
| THC | TENET HEALTHCARE CORP | 1.60% |
| SPRY | ARS PHARMACEUTICALS | 1.59% |
| FULC | FULCRUM THERAPEUTICS, INC. | 1.56% |
| BRKR | BRUKER CORP | 1.54% |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.52% |
| UNH | UNITEDHEALTH GROUP INC | 1.51% |
| SNY | SANOFI- AVENTIS- ADR | 1.50% |
| PRQR | PROQR THERAPEUTICS NV | 1.50% |
| ELV | ELEVANCE HEALTH INC | 1.49% |
| MDT | MEDTRONIC PLC | 1.48% |
| URGN | UROGEN PHARMA LTD. | 1.47% |
| SYK | STRYKER CORP | 1.47% |
| VCEL | VERICEL CORP | 1.45% |
| AVTX | AVALO THERAPEUTICS INC | 1.44% |
| DHR | DANAHER CORP | 1.44% |
| WAT | WATERS CORP | 1.42% |
| RGEN | REPLIGEN CORP | 1.41% |
| ABBV | ABBVIE INC | 1.41% |
| NEO | NEOGENOMICS INC | 1.37% |
| HUM | HUMANA INC | 1.34% |
| ISRG | INTUITIVE SURGICAL INC | 1.34% |
| ABT | ABBOTT LABORATORIES | 1.28% |
| IRON | DISC MEDICINE INC | 1.27% |
| LLY | ELI LILLY CORP | 1.25% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 1.24% |
| ICLR | ICON PLC | 1.19% |
| BSX | BOSTON SCIENTIFIC | 1.01% |
| PODD | INSULET CORP | 0.97% |
| JANX | JANUX THERAPEUTICS INC | 0.84% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) click here or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Private Investments, LLC, Guggenheim Investments Loan Advisors, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, and GS GAMMA Advisors, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
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