| Symbol | Company | Weighting |
|---|---|---|
| KRRO | KORRO BIO | 3.64% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 2.66% |
| EWTX | EDGEWISE THERAPEUTICS | 2.55% |
| RVMD | REVOLUTION MEDICINES INC | 2.53% |
| SNDX | SYNDAX PHARMACEUTICALS, INC. | 2.51% |
| XENE | XENON PHARMACEUTICALS | 2.43% |
| OCS | OCULIS HOLDING AG | 2.41% |
| BMY | BRISTOL MYERS SQUIBB CO | 2.29% |
| MRK | MERCK & CO. NEW | 2.27% |
| AXSM | AXSOME THERAPEUTICS INC. | 2.15% |
| ALKS | ALKERMES INC | 2.11% |
| PCVX | VAXCYTE INC | 2.08% |
| DNLI | DENALI THERAPEUTICS INC. | 1.97% |
| EYPT | EYEPOINT INC | 1.96% |
| AVTX | AVALO THERAPEUTICS INC | 1.93% |
| AZN | ASTRAZENECA PLC | 1.93% |
| IONS | IONIS PHARMACEUTICALS INC | 1.84% |
| TSHA | TAYSHA GENE THERAPIES I | 1.82% |
| MCK | MCKESSON CORP | 1.78% |
| IDYA | IDEAYA BIOSCIENCES, INC | 1.77% |
| TNDM | TANDEM DIABETES CARE INC | 1.76% |
| GEHC | GE HEALTHCARE TECHNOLOGIES INC | 1.73% |
| SPRY | ARS PHARMACEUTICALS | 1.72% |
| ZTS | ZOETIS INC | 1.71% |
| HCA | HCA HOLDINGS INC | 1.69% |
| ALC | ALCON INC | 1.69% |
| ARQT | ARCUTIS BIOTHERAPEUTICS | 1.68% |
| DYN | DYNE THERAPEUTICS, INC. | 1.68% |
| THC | TENET HEALTHCARE CORP | 1.67% |
| RVTY | REVVITY INC | 1.65% |
| SNY | SANOFI- AVENTIS- ADR | 1.60% |
| TVTX | TRAVERE THERAPEUTICS INC | 1.59% |
| MDT | MEDTRONIC PLC | 1.57% |
| ABBV | ABBVIE INC | 1.56% |
| ELV | ELEVANCE HEALTH INC | 1.54% |
| SYK | STRYKER CORP | 1.53% |
| BRKR | BRUKER CORP | 1.51% |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.51% |
| FULC | FULCRUM THERAPEUTICS, INC. | 1.51% |
| DHR | DANAHER CORP | 1.48% |
| VCEL | VERICEL CORP | 1.43% |
| ISRG | INTUITIVE SURGICAL INC | 1.42% |
| UNH | UNITEDHEALTH GROUP INC | 1.41% |
| LLY | ELI LILLY CORP | 1.40% |
| WAT | WATERS CORP | 1.39% |
| URGN | UROGEN PHARMA LTD. | 1.39% |
| ABT | ABBOTT LABORATORIES | 1.38% |
| PRQR | PROQR THERAPEUTICS NV | 1.38% |
| RGEN | REPLIGEN CORP | 1.35% |
| NEO | NEOGENOMICS INC | 1.31% |
| SLNO | SOLENO THERAPEUTICS INC | 1.29% |
| HUM | HUMANA INC | 1.28% |
| IRON | DISC MEDICINE INC | 1.25% |
| ICLR | ICON PLC | 1.21% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 1.13% |
| PODD | INSULET CORP | 1.07% |
| BSX | BOSTON SCIENTIFIC | 1.03% |
| JANX | JANUX THERAPEUTICS INC | 0.87% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) click here or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, GS GAMMA Advisors, LLC, and Guggenheim Private Investments, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
© 2026 Guggenheim Investments. All Rights Reserved.
Research our firm with FINRA Broker Check.
• Not FDIC Insured • No Bank Guarantee • May Lose Value
This website is directed to and intended for use by citizens or residents of the United States of America only. The material provided on this website is not intended as a recommendation or as investment advice of any kind, including in connection with rollovers, transfers, and distributions. Such material is not provided in a fiduciary capacity, may not be relied upon for or in connection with the making of investment decisions, and does not constitute a solicitation of an offer to buy or sell securities. All content has been provided for informational or educational purposes only and is not intended to be and should not be construed as legal or tax advice and/or a legal opinion. Always consult a financial, tax and/or legal professional regarding your specific situation. Investing involves risk, including the possible loss of principal.