| Symbol | Company | Weighting |
|---|---|---|
| RVMD | REVOLUTION MEDICINES INC | 3.63% |
| KRRO | KORRO BIO | 3.60% |
| ARWR | ARROWHEAD PHARMACEUTICALS INC | 2.91% |
| TSHA | TAYSHA GENE THERAPIES I | 2.61% |
| EWTX | EDGEWISE THERAPEUTICS | 2.33% |
| OCS | OCULIS HOLDING AG | 2.33% |
| XENE | XENON PHARMACEUTICALS | 2.29% |
| AXSM | AXSOME THERAPEUTICS INC. | 2.26% |
| SNDX | SYNDAX PHARMACEUTICALS, INC. | 2.17% |
| BMY | BRISTOL MYERS SQUIBB CO | 2.11% |
| PCVX | VAXCYTE INC | 2.04% |
| TVTX | TRAVERE THERAPEUTICS INC | 2.03% |
| MRK | MERCK & CO. NEW | 2.02% |
| ALKS | ALKERMES INC | 2.01% |
| EYPT | EYEPOINT INC | 1.99% |
| DNLI | DENALI THERAPEUTICS INC. | 1.96% |
| UNH | UNITEDHEALTH GROUP INC | 1.84% |
| ELV | ELEVANCE HEALTH INC | 1.82% |
| SLNO | SOLENO THERAPEUTICS INC | 1.81% |
| AZN | ASTRAZENECA PLC | 1.75% |
| URGN | UROGEN PHARMA LTD. | 1.73% |
| IONS | IONIS PHARMACEUTICALS INC | 1.72% |
| TNDM | TANDEM DIABETES CARE INC | 1.71% |
| ZTS | ZOETIS INC | 1.67% |
| MCK | MCKESSON CORP | 1.66% |
| ALC | ALCON INC | 1.65% |
| SPRY | ARS PHARMACEUTICALS | 1.65% |
| DYN | DYNE THERAPEUTICS, INC. | 1.65% |
| HUM | HUMANA INC | 1.63% |
| GEHC | GE HEALTHCARE TECHNOLOGIES INC | 1.61% |
| ARQT | ARCUTIS BIOTHERAPEUTICS | 1.59% |
| RVTY | REVVITY INC | 1.57% |
| IDYA | IDEAYA BIOSCIENCES, INC | 1.55% |
| VCEL | VERICEL CORP | 1.53% |
| THC | TENET HEALTHCARE CORP | 1.53% |
| HCA | HCA HOLDINGS INC | 1.51% |
| SNY | SANOFI- AVENTIS- ADR | 1.50% |
| NEO | NEOGENOMICS INC | 1.49% |
| BRKR | BRUKER CORP | 1.48% |
| FULC | FULCRUM THERAPEUTICS, INC. | 1.47% |
| MDT | MEDTRONIC PLC | 1.46% |
| AVTX | AVALO THERAPEUTICS INC | 1.46% |
| SYK | STRYKER CORP | 1.45% |
| TMO | THERMO FISHER SCIENTIFIC INC | 1.41% |
| ABBV | ABBVIE INC | 1.40% |
| ISRG | INTUITIVE SURGICAL INC | 1.39% |
| DHR | DANAHER CORP | 1.36% |
| WAT | WATERS CORP | 1.36% |
| RGEN | REPLIGEN CORP | 1.31% |
| IRON | DISC MEDICINE INC | 1.27% |
| RARE | ULTRAGENYX PHARMACEUTICAL INC | 1.27% |
| LLY | ELI LILLY CORP | 1.25% |
| ABT | ABBOTT LABORATORIES | 1.24% |
| PRQR | PROQR THERAPEUTICS NV | 1.17% |
| ICLR | ICON PLC | 1.09% |
| BSX | BOSTON SCIENTIFIC | 0.95% |
| PODD | INSULET CORP | 0.92% |
| JANX | JANUX THERAPEUTICS INC | 0.85% |
Read a prospectus and summary prospectus (if available) carefully before investing. It contains the investment objective, risks charges, expenses and the other information, which should be considered carefully before investing. To obtain a prospectus and summary prospectus (if available) click here or call 800.820.0888.
Investing involves risk, including the possible loss of principal.
Guggenheim Investments represents the following affiliated investment management businesses of Guggenheim Partners, LLC: Guggenheim Partners Investment Management, LLC, Security Investors, LLC, Guggenheim Funds Distributors, LLC, Guggenheim Funds Investment Advisors, LLC, Guggenheim Corporate Funding, LLC, Guggenheim Wealth Solutions, LLC, Guggenheim Private Investments, LLC, Guggenheim Investments Loan Advisors, LLC, Guggenheim Partners Europe Limited, Guggenheim Partners Japan Limited, and GS GAMMA Advisors, LLC. Securities offered through Guggenheim Funds Distributors, LLC.
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